Peptide Academy · Sexual Health
Also known as KISS1 peptide / Metastin
Educational research summary, not medical advice. Many compounds here are not approved for human use. Talk to a licensed clinician before making any health decision.
The Peptide Academy is free to read. Members also get the research protocols for Kisspeptin, dose and vial tracking, and an AI Advisor with cited sources. Try it all free for 7 days, no card needed.
Start my free 7-day trialThe master upstream regulator of the reproductive hormone axis, studied for fertility and libido.
Activates KISS1R on hypothalamic GnRH neurons, triggering the entire LH/FSH reproductive cascade.
Short — minutes
Investigational; tachyphylaxis occurs with continuous exposure.
Common side effects
Histamine reactions
Flushing is common; site itching occasionally.
Common fixes
Stop and get help
Basis: Prescribing information. Educational only, not medical advice.
Hormone treatments (testosterone, estrogen, GnRH drugs, fertility medicines)
Kisspeptin works through the same reproductive hormone axis; effects can overlap or cancel out.
Hormone lab tests
LH, FSH and sex hormone results can shift around doses.
Everything else you take, including supplements
Bring a full list of medicines and supplements to your pharmacist or clinician before starting.
Basis: No interaction studies; concerns follow from its action on the GnRH axis. Educational only, not medical advice. Never stop or change a prescribed medicine without your prescriber.
Protocols & tracking are members-only
Members see the research protocols for Kisspeptin, plan schedules, track every dose and vial, and ask the AI Advisor questions with cited sources. Try every Researcher feature free for 7 days, no card needed.